问题描述：
英语翻译
Effectively,by making a change in the primer,these experiments
introduced single mismatches in the primer-genomic DNA duplex
at both of the sites that define a DNA segment,and detectable
amplification was prevented.By inference,a single base change
in the genome may also prevent amplification by introducing a
mismatch at just one end of a DNA segment.
Effectively,by making a change in the primer,these experiments
introduced single mismatches in the primer-genomic DNA duplex
at both of the sites that define a DNA segment,and detectable
amplification was prevented.By inference,a single base change
in the genome may also prevent amplification by introducing a
mismatch at just one end of a DNA segment.
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