that is his family photo.

that is his family photo.(那是他的全家福）
that is the photo of his family（那是他的全家福,近义句）
that is his family photo（还可理解为那是他的家庭照片）
that is the photo of his family（还可理解为那张照片是关于他的家庭）
两句意思皆为那是他的全家福.