英语翻译Binding Interface Between \1C209 P4-P6 and Fab2.Fab2 bin

英语翻译
Binding Interface Between \1C209 P4-P6 and Fab2.Fab2 binds to
\1C209 P4-P6 with an exceptionally large buried surface area (Fig.
4A),1,316 Å2 (on the Fab side alone),which is almost twice as large
as that of most Fab–protein antigen interfaces (777\3135 Å2) (35).
Consistent with the extensive surface burial,residues from all six
CDRs and some scaffold residues form the interface (Fig.4 and SI Fig.11).Superposition of the variable domains reveals significant
differences in the main chain conformations of CDR-H3,L2 and
H2 compared with the parent (32) Fab-4D5,illustrating the conformational
plasticity of the hypervariable regions (Fig.4B).Within
the Fab–RNA interface,CDR-H3 and L2 make direct contact with
both P5a and P5c stems and contribute most to the buried surface
area:34% and 29%,respectively (Fig.4C).This observation
suggests that CDR-H3 and L2 likely play significant roles in the
recognition of \1C209 P4-P6,even though L2 was not diversified in
the library
这篇论文里面是有插图的,括号里面的fig就是指里面的图片,没必要注意.我要求不高,能把大概意思说出来就行