---How are you getting alone with your business?--I'm glad t

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本句意思是：-你生意怎么样?-我很高兴地说它（）.
高兴,那说明生意不错,或在好转.
pick up: 好转; 恢复
例句：
1. When is the weather going to pick up? It's been bad for weeks.
天气什么时候转好?几周来一直很糟糕.
2. Trade has been slack for the past six months, but it is now picking up.
在过去六个月中贸易一直不景气, 但现在状况正在好转.
turn up: 开大、翻起；出现
例：
1. Please turn the radio up a little.请把收音机开大一点.
2. He turned up the collar of his coat. 他把大衣领子翻起来.
take up: 拿起、抱起；占去；接受(提议) ；继续
例句：
1. He took up telephone receiver and began to dial. 他拿起电话听筒开始拨号码.
2. She takes up a child under each arm. 她一手抱起一个孩子.
3. I won't take up much of your time. 我不会占用你很多时间.
4. I'd like to take up your offer of a ride into town. 我愿接受你的邀请, 搭你的车进城.
5. I put the telephone down and took up my work again. 我放下电话继续干我的活.
break up: 结束、分手、散会；破裂、破碎、分解；放假；(使)极其焦虑和痛苦,(使)开心, 发笑
例句：
1. The party breaks up and the neighbors hurry home. 宴会就此结束, 邻居们匆匆地赶回家去.
2. They break up the meeting. 他们散会了.
3. It was money trouble that broke up their marriage. 他们因钱的问题婚姻才破裂的.
4. When does the ice break up on the river? 河里的冰什么时候融化?
5. We break up next week. 我们下周放假.
6. She broke up at the bad news. 听到那个不幸的消息使她感到非常痛苦.
7. His story broke me up. I couldn't stop laughing. 他的故事真逗, 我简直笑破了肚皮.
从以上意思和例句来看,只有pick up能表示好转,符合句意,是正确的!