是的. be in charge of 通常是“掌管、负责、”之意,有主动意味,主语常是人,比如: He was in charge of the shop while the manager was away. 经理不在的时候,他掌管这个店. be in the charge of 表“由……掌管、负责”之意,有被动的意味,in还可以用under代替,比如: These patients are in(或under) the charge of Dr.Wilson. 这些病人是威尔逊医生负责治疗的.