问题描述:
英语翻译
The sulfation of a water-insoluble Ganoderma lucidum polysaccharide (GLP) was successfully
carried out with chlorosulfonic acid-pyridine in dimethyl formamide to prepare three sulfated GLP
derivatives,named sGLP1,sGLP2,and sGLP3.The chemical structure of the sulfated GLP was
confirmed by Fourier transform infrared and 13C NMR analyses.The sGLPs were evaluated for their
water solubility,degree of substitution (DS),antioxidant properties,and bile acid-binding capacities.
The results showed that sulfation improved the water solubility of GLP and increased its scavenging
capacities against hydroxyl and superoxide anion radicals,hydrogen peroxide-scavenging activity,
Fe(II) chelating ability,reducing power,and bile acid-binding capacities.It was also observed that
the DS may influence the physicochemical and functional properties of sGLPs.For instance,the
sulfated GLP with the lowest DS had the greatest bile acid-binding capacity,and the sGLP that had
the highest DS showed the lowest bile acid-binding ability under the experimental conditions.The
results from this study suggested that sulfation is a possible approach to obtain novel water-soluble
derivatives of GLP with improved physicochemical,functional,and biological properties for potential
utilization in functional foods or supplemental products.
The sulfation of a water-insoluble Ganoderma lucidum polysaccharide (GLP) was successfully
carried out with chlorosulfonic acid-pyridine in dimethyl formamide to prepare three sulfated GLP
derivatives,named sGLP1,sGLP2,and sGLP3.The chemical structure of the sulfated GLP was
confirmed by Fourier transform infrared and 13C NMR analyses.The sGLPs were evaluated for their
water solubility,degree of substitution (DS),antioxidant properties,and bile acid-binding capacities.
The results showed that sulfation improved the water solubility of GLP and increased its scavenging
capacities against hydroxyl and superoxide anion radicals,hydrogen peroxide-scavenging activity,
Fe(II) chelating ability,reducing power,and bile acid-binding capacities.It was also observed that
the DS may influence the physicochemical and functional properties of sGLPs.For instance,the
sulfated GLP with the lowest DS had the greatest bile acid-binding capacity,and the sGLP that had
the highest DS showed the lowest bile acid-binding ability under the experimental conditions.The
results from this study suggested that sulfation is a possible approach to obtain novel water-soluble
derivatives of GLP with improved physicochemical,functional,and biological properties for potential
utilization in functional foods or supplemental products.
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