问题描述:
机械英语翻译
The above methods are all based on image analysis. There are
several traditional, non-image based methods for quantification of
internal granule structure. These methods include pycnometry [27],
mercury porosimetry [19,28,29], nitrogen adsorption technique or
BET analysis [28,30] and Inverse Gas Chromatography, IGC, [31].
Acquiring the internal granule structure by modern methods, such as
image-based techniques, is often costly due to operating and capital
costs of equipment such as X-ray micro-tomography (XMT), Magnetic
Resonance Imaging (MRI), and Transmission Electron Microscopy
(TEM). However, these are more accurate and give more information
which cannot otherwise be obtained by the traditional methods. XMT
has been used in the field of granulation technology for analysis of the
internal structure of granules [19] and tablets [32], external particle
shape [33] and characterisation of agglomerate structure for DEM
simulations [14].An important challenge of the granulation technology is to
produce consistent granule structure and shape which in turn lead
to more uniform properties such as strength and dissolution rate. This
is difficult without introducing a method to quantify the granule
structure. In this paper we use some structure descriptors such as
chord length distribution and phase function to enable quantification
of internal structure of granules.
The characterisation of granule strength [34–39] and structure [14]
has previously been reported. However, there is no work on the effect
of different operating conditions, such as impeller speed on the
internal granule structure. The objective of this work is to acquire the
internal structure of granules by high resolution X-ray microtomography
and to analyse it using a software package developed
by Stepanek et al. [40]. The granules used in this work were produced
at three different impeller speeds in a high shear granulator. The
measurement of strength of these granules by side crushing test
method has previously been reported [38,39,41]. An attempt has been
made to relate the acquired structure to granule strength.
不怎么通顺呀,要是满意的话,可以追加分的
The above methods are all based on image analysis. There are
several traditional, non-image based methods for quantification of
internal granule structure. These methods include pycnometry [27],
mercury porosimetry [19,28,29], nitrogen adsorption technique or
BET analysis [28,30] and Inverse Gas Chromatography, IGC, [31].
Acquiring the internal granule structure by modern methods, such as
image-based techniques, is often costly due to operating and capital
costs of equipment such as X-ray micro-tomography (XMT), Magnetic
Resonance Imaging (MRI), and Transmission Electron Microscopy
(TEM). However, these are more accurate and give more information
which cannot otherwise be obtained by the traditional methods. XMT
has been used in the field of granulation technology for analysis of the
internal structure of granules [19] and tablets [32], external particle
shape [33] and characterisation of agglomerate structure for DEM
simulations [14].An important challenge of the granulation technology is to
produce consistent granule structure and shape which in turn lead
to more uniform properties such as strength and dissolution rate. This
is difficult without introducing a method to quantify the granule
structure. In this paper we use some structure descriptors such as
chord length distribution and phase function to enable quantification
of internal structure of granules.
The characterisation of granule strength [34–39] and structure [14]
has previously been reported. However, there is no work on the effect
of different operating conditions, such as impeller speed on the
internal granule structure. The objective of this work is to acquire the
internal structure of granules by high resolution X-ray microtomography
and to analyse it using a software package developed
by Stepanek et al. [40]. The granules used in this work were produced
at three different impeller speeds in a high shear granulator. The
measurement of strength of these granules by side crushing test
method has previously been reported [38,39,41]. An attempt has been
made to relate the acquired structure to granule strength.
不怎么通顺呀,要是满意的话,可以追加分的
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