in the hope of ,with the hope of 怎样区分

你看这两个介词的意思就不一样,in表示在hope其中,with表示hope随身,两个状态不一样.
我试举两个例子
In the hope of creation,he leads a hardworking life.
With the hope of escaping,he jumped out of the window.
主句的动作状态持续不同,后句是眼下的,前句是长久的.